ICSG2006 main conference program
>>Sunday, October 22
>>Monday, October 23
>>Tuesday, October 24
>>Wednesday, October 25
>>Thursday, October 26
  Sunday, October 22 
 1:45 – 3:45pm
ISGO Open Executive Committee & Advisory Panel Meeting (Building 1)
 4:00 – 4:30pm
Opening Ceremony
 4:30 – 6:30pm
PL1: Plenary Lectures (Session 1)
Session chairs: Dong-Cai Liang / David Stuartd
 4:30pm
Wayne A. Hendrickson
Columbia University, USA
 
 
"Origins and Destinations of Structural Genomics"
 5:20pm
Janet Thornton
European Bioinformatics Institute, UK
 
"From protein structure to biological function: progress and limitations"
 5:50pm
Tom Blundell
University of Cambridge, UK
 
"Structural Proteomics and Chemical Space: the New Dimensions of Drug Discovery"
 7:00 – 9:00pm
Welcome Reception (Friendship Palace)
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  Monday, October 23 
 8:00 – 10:00am
PU: Protein Universe (Structural Bioinformatics)
Session chairs: Luhua Lai / Joel Janin
 8:00am
John Moult
UMBI, USA
 
"Structure and function of alternatively spliced proteins"
 8:25am
Sung-Hou Kim
UC Berkeley, USA
 
"Structural and Functional Mapping of the Protein Structure Universe"
 8:50am
Steven Brenner
UC Berkeley, USA
 
"Expectations, outcomes & impacts of structural genomics"
 9:15am
Alexey Murzin
University of Cambridge, UK
 
"Impact of Structural Genomics on the Discovery of Protein Relationships"
 9:40am
Jie Liang
University of Illinois at Chicago, USA
 
"Evolutionary matching of surface patterns for predicting protein functions and binding specificities"
 10:00 – 10:30am
Coffee break
 10:30 – 12:00pm
LSG1: Large-scale Structural Genomics (Session 1) Session chairs: Zihe Rao / Kunio Miki
 10:30am
Ian Wilson
JCSG, USA
 
"The JCSG high throughput production pipeline for Structural Genomics"
 11:00am
David Stuart
University of Oxford, UK
 
"Structural Proteomics in Europe - the Second Phase"
 11:30am
Shigeyuki Yokoyama
RIKEN GSC, Japan
 
"RIKEN Structural Genomics/Proteomics Initiative"
 12:00 – 2:00 pm
Lunch (Friendship Palace); Poster + Exhibition Viewing
 2:00 – 3:30pm
TSG1: Technologies for Structural Genomics & Structural Biology (Session 1)
Session chairs: Weimin Gong / Shigeyuki Yokoyama
 2:00pm
Aled Edwards
SGC Toronto, Canada
"Stargazing and Functional Annotation"
 2:30pm
Soichi Wakatsuki
Photon Factory, Japan
"Synchrotron Technologies for Target-Oriented Structural Proteomics of Protein Transport and Glycosylation"
 3:00pm
Wladek Minor
University of Virginia, USA
"Quick Solution of Difficult Structures is Not Necessarily an Oxymoron"
 3:30 – 4:00pm
Coffee break
 4:00 – 6:00pm
FSP1: Focused Structural Proteomics (Session 1)
Session chairs: Bi-Cheng Wang / James (Zhi-Jie) Liu
 4:00pm
Dino Moras
University of Strasbourg, France
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(size 16.8MB)
"Transcription regulation by Nuclear Receptors: an example of Focused Structural Genomics"
 4:25pm
John Markley
University of Wisconsin, USA
"Center for Eukaryotic Structural Genomics"
 4:50pm
Bi-Cheng Wang
University of Georgia, USA
"A Report on the Global Structural Proteomics Initiative and UGAòfs Structural Genomics of Non-Pfam Targets"
 5:15pm
Michael Parker
University of Melbourne, Australia
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(size 7.3MB)
"The challenges of extracting function from structure"
 5:40pm
Min Li
UCSF, USA
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(size 9.8MB)
"Expression, Purification, and Crystallization of Membrane Proteins"
 7:00 – 9:00 pm
FESP: Forum for European Structural Proteomics (Building 1)
Lucia Banci (Italy)
Josefina Enfedaque (European Commission)
Udo Heinemann (Germany)
John Norvell (USA)
Zihe Rao (China)
Joel L. Sussman (Israel)
Shigeyuki Yokoyama (Japan)
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  Tuesday, October 24 
 8:00 – 10:00am
TSG2: Technologies for Structural Genomics and Structural Biology (Session 2)
Session chairs: Rongguang Zhang / Tom Terwilliger
 8:00am
Ray Stevens
The Scripps Research Institute, USA
"The JCIMPT - Innovative New Technologies for Membrane Protein Structural Biology"
 8:30am
Hiroaki Imataka
RIKEN GSC, Japan
"A hybridoma-based cell-free system that efficiently synthesizes biologically active glycoprotein complexes"
 9:00am
Geoffrey Waldo
Los Alamos National Laboratory, USA
"GFP technology for engineering protein folding and finding soluble domains"
 9:30am
Scott Lesley
JCSG, USA
"Salvaging problematic targets: lessons learned from structural genomics"
 10:00 – 10:30am
Coffee break
 10:30 – 12:00pm
LSG2: Large-scale Structural Genomics (Session 2)
Session chairs: Aled Edwards / Liang Tong
 10:30am
Andrzej Joachimiak
MCSG, USA
"Structural Genomics - Expanding Protein Fold Space and Discovering Function"
 11:00am
Gaetano Montelione
Rutgers University and Northeast Structural Genomics Consortium, USA
"Structural Proteomics of Eukaryotic Domain Families"
 11:30am
Cheryl Arrowsmith
SGC Toronto, Canada
"The Structural Genomics Consortium: Structural biology and chemistry of human gene families"
 12:00 – 2:00 pm
Lunch (Friendship Palace); Poster + Exhibition Viewing
 2:00 – 4:00pm
SGP: Structural Genomics Policy
Session chairs: Yigong Shi / Udo Heinemann
 2:00pm
John Norvell
NIGMS, NIH, USA
"Protein Structure Initiative: Progress and Plans"
 2:25pm
Josefina Enfedaque
European Commission
"Large-scale data gathering and technology development initiatives in the EU: from structural genomics to systems biology"
 2:50pm
Helen Berman
Rutgers University, USA
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(size 2.3MB)
"Resources for Structural Genomics from the RCSB PDB"
 3:15pm
Tom Terwilliger
Los Alamos National Laboratory, USA
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(size 124KB)
"ISGO: The International Structural Genomics Organization"
 3:40pm
Weimin Gong
Institute of Biophysics, CAS, China
"The China National Human Liver Structural Proteomics Project – part of the international HUPO program"
 4:00 – 4:30pm
Coffee break
 4:30 – 6:00pm
TSG3: Technologies for Structural Genomics and Structural Biology (Session 3)
Session chairs: Bin Xia / Liwen Niu
 4:30pm
Thomas Szyperski
New York at Buffalo, USA
"Rapid NMR data collection for structural genomics: G-matrix FT NMR"
 5:00pm
Robert Kaptein
Utrecht University, Netherlands
"High-throughput methods for NMR structural analysis of proteins and complexes"
 5:30pm
Yunyu Shi
USTC, China
"Protein-protein interaction studied by NMR"
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  Wednesday, October 25 
 8:00 – 10:05am
FSP2: Focused Structural Proteomics (Session 2)
Session chairs: Samar Hasnain / Jennifer Martin
 8:00am
Lance Stewart
deCODE biostructures, Inc.
"The NIGMS-NCRR PSI-2 Accelerated Technologies Center for Gene to 3D Structure - ATCG3D"
 8:25am
Udo Heinemann
Max Delbrueck Center for Molecular Medicine, Germany
"Structural Genomics from Proteins to Protein Complexes: The Transport Protein Particle (TRAPP)"
 8:50am
Mirek Cygler
NRC Canada
"Medium-throughput structural biology of bacterial proteins at the MKBSGI: a five-year perspective"
 9:15am
Liang Tong
Columbia University, USA
"Functional insights from NESG structures"
 9:40am
Ming Luo
University of Alabama, USA
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(size 8.1MB)
"A Structural Genomics Approach to Study Novel Human Proteins ".
 10:05 – 10:35am
Coffee break
 10:35 – 12:40pm
LSG1: Large-scale Structural Genomics (Session 1)
Session chairs: Zihe Rao / Kunio Miki
 10:35am
Ted Baker
University of Auckland, New Zealand
"Investigations of TB Biology and Potential New Drug Targets in a Targeted Application of Structural Genomics"
 11:00am
Samar Hasnain
Daresbury, UK
"Metalloproteomics: Problems and Challenges"
 11:25am
Jennifer Martin
University of Queensland, Australia
"Focusing on therapeutic outcomes: cherry-picking macrophage proteins for structural genomics"
 11:50am
Isao Tanaka
Hokkaido University, Japan
"Structural basis for amino acid conversion on tRNA"
 12:15pm
Wenqing Xu
University of Washington, USA
"Crystallographic studies of proteins and protein complexes in Wnt signaling"
 12:40 – 2:00 pm
Lunch (Friendship Palace); Poster + Exhibition Viewing
 2:00 – 4:00pm
MP: Membrane Proteins Session chairs: Neil Isaacs / Wenrui Chang
 2:00pm
Hartmut Michel
MBIBP, Germany
"Structural membrane genomics versus structural membrane proteomics with emphasis on Aquifex aeolicus"
 2:30pm
Neil Isaacs
University of Glasgow, UK
"The Membrane Protein Structure Initiative (MPSI)"
 3:00pm
James H. Naismith
University of St. Andrews, UK
"The mechanism of carbohydrate capsule export"
 3:30pm
Youxing Jiang
University of Texas Southwestern, USA
"Structural basis of ligand-gating in the MthK channel"
 4:00 – 4:30pm
Coffee break
 4:30 – 6:00pm
PC: Protein Complexes Session chairs: Wenqing Xu / Fei Sun
 4:30pm
Kunio Miki
Kyoto University, Japan
"Molecular Assembly of Extracellular Giant Hemoglobin"
 5:00pm
Joel Janin
Paris-Sud Yeast Structural Genomics, France
"Yeast Structural Genomics: The pilot-project and beyond"
 5:30pm
Fei Sun
Institute of Biophysics, CAS, China
>>pdf.gz
(size 5.8MB)
"Crystal structure of mitochondrial respiratory membrane protein Complex II"
 7:00 – 9:00pm
Conference Banquet (Friendship Palace)
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  Thursday, October 26 
 8:15 – 8:55am
PL2: Plenary Lectures (Session 2)
Session chair: Zihe Rao
 8:15am
Timothy Springer
Harvard Medical School, USA
"Integrin allostery and bidirectional signal transmission across the plasma membrane"
 9:00 – 10:00am
PIA1: Pharmaceutical and Industrial Applications (Session 2)
Session chairs: Peter Kuhn / Cheng Yang
 9:00am
Stephen Burley
SGX Pharmaceuticals, Inc., USA
"Fragment-based discovery of BCR-ABL inhibitors for treatment of chronic myelogenous leukemia"
 9:30am
Duncan McRee
ActiveSight, USA
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(size 5.1MB)
"Application of high-throughput methodology to human drug targets"
 10:00 – 10:30am
Coffee break
 10:30 – 12:00pm
PIA2: Pharmaceutical and Industrial Applications (Session 2)
Session chairs: Jianping Ding / Xiaodong Su
 10:30am
Peter Colman
Walter and Eliza Hall Institute, Austria
"Structure, function and manipulation of the interactions between pro-apoptotic molecules with the Bcl-2 protein family"
 11:00am
Horst Hemmerle
Lilly Research Labs, Indianapolis, USA
"Structure-based Drug Discovery at Lilly"
 11:30am
Yuan-Hua Ding
Pfizer Global Research and Development, USA
"Building an Integrated Structural Biology Platform to Address Key Issues in Drug Discovery"
 12:00 – 2:00 pm
Lunch (Friendship Palace);
Poster + Exhibition Viewing
 2:00 – 3:15pm
FSG: Future Opportunities for Structural Genomics
Session chairs: Yuan-Hua Ding / Wenrui Chang
 2:00pm
Lucia Banci
University of Florence, Italy
>>ppt.gz
(size 13.8MB)
"A part of the interactome is metal mediated: a structural genomics perspective"
 2:25pm
Bostjan Kobe
University of Queensland, Australia
>>ppt.gz
(size 4.2MB)
"Structure determination using a combination of chemical cross-linking, mass spectrometry and molecular modeling"
 2:50pm
Zhi-Jie Liu
SECSG, USA & Institute of Biophysics, CAS, China
"Crystallography in the Structural Genomics of Non-Pfam Targets"
 3:15 – 3:45pm
Coffee break
 3:45 – 5:35pm
SGD: Structural Genomics and Disease Session chairs: Ray Stevens / David Stuart
 3:45pm
Renaud Vincentelli and Bruno Canard
University of Marseilles, France
>>pdf
(size 1.5MB)
"Anticipating the scientific response to emerging viruses: the VIZIER project"
 4:15pm
Peter Kuhn
The Scripps Research Institute, USA
"The FSPS - Functional and Structural Proteomics of SARS CoV related proteins"
 4:45pm
Zihe Rao
Tsinghua-Nankai-IBP Joint Research Group for Structural Biology, China
"Structural insights into SARS coronavirus replication machinery"
 5:15pm
Fei Philip Gao
Florida State University, USA
>>ppt.gz
(size 51.8MB)
"Structural Genomics of Integral Membrane Proteins from Mycobacterium tuberculosis"
 5:35 – 6:05pm
Closing Remarks
Zihe Rao
Shigeyuki Yokoyama
David Stuart
Tom Terwilliger
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